Mannosylerythritol lipid increases levels of galactoceramide in and neurite outgrowth from PC12 pheochromocytoma cells
โ Scribed by Miki Shibahara; Xiaoxian Zhao; Yoko Wakamatsu; Nobuhiko Nomura; Tadaatsu Nakahara; Chunyuan Jin; Hideyuki Nagaso; Takehide Murata; Kazunari K. Yokoyama
- Book ID
- 110259366
- Publisher
- Springer
- Year
- 2000
- Tongue
- English
- Weight
- 86 KB
- Volume
- 33
- Category
- Article
- ISSN
- 0920-9069
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Mn 2ุ treatment has been shown to promote neurite outgrowth in rat pheochromocytoma (PC12) cells in a time-and dose-dependent manner. This process is mediated through the interactions of extracellular matrix (ECM) proteins and integrin receptors. Studies were performed to determine whether the phosp
As a neurotransmitter and neuromodulator, serotonin (5-HT) influences neuronal outgrowth in the nervous systems of several species. In PC12 cells, 5-HT is known to have neuritogenic effects, although the signal transduction pathway responsible for these effects is not understood. In this study, we h