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Mannose receptor dependent uptake of a ricin a chain - antibody conjugate by rat liver non-parenchymal cells

โœ Scribed by Nan R. Worrell; David N. Skilleter; Alan J. Cumber; Roger J. Price


Book ID
115759956
Publisher
Elsevier Science
Year
1986
Tongue
English
Weight
291 KB
Volume
137
Category
Article
ISSN
0006-291X

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๐Ÿ“œ SIMILAR VOLUMES


Mannose receptor dependent uptake of ric
โœ Fabio Riccoboni; Maria L. Fiani ๐Ÿ“‚ Article ๐Ÿ“… 1996 ๐Ÿ› Elsevier Science ๐ŸŒ English โš– 526 KB

The ricin A chain, the toxic subunit of ricin, consists of two forms which differ in sugar content. The major component A1 contains one high mannose chain while the minor component A2 contains an additional high mannose chain. Endocytosis of this toxin occurs in macrophages via the mannose receptor.