Mannose receptor dependent uptake of ric
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Fabio Riccoboni; Maria L. Fiani
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Article
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1996
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Elsevier Science
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English
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The ricin A chain, the toxic subunit of ricin, consists of two forms which differ in sugar content. The major component A1 contains one high mannose chain while the minor component A2 contains an additional high mannose chain. Endocytosis of this toxin occurs in macrophages via the mannose receptor.