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Mannose binding lectin gene polymorphisms and asthma

✍ Scribed by X. Wang; J. Saito; Y. Tanino; T. Ishida; T. Fujita; M. Munakata


Book ID
108688029
Publisher
John Wiley and Sons
Year
2007
Tongue
English
Weight
120 KB
Volume
37
Category
Article
ISSN
0954-7894

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Mannose-binding lectin (MBL) is a C-type lectin produced mainly by the liver that binds to a wide range of pathogens. Polymorphisms at the promoter and exon 1 of the MBL2 gene are responsible for low serum levels of MBL and have been associated with an increased risk of infections. We prospectively