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Mannich reactions of furan and 2-methylfuran using pre-formed imonium salts

✍ Scribed by Harry Heaney; George Papageorgiou; Robert F. Wilkins


Book ID
104220033
Publisher
Elsevier Science
Year
1988
Tongue
French
Weight
179 KB
Volume
29
Category
Article
ISSN
0040-4039

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✦ Synopsis


Good yields of 2-dialkylamincmethylfurans are obtained when N,N-dialkylmethyleneimonium chlorides are allowed to interact with furan in acetonitrile at room temperature; similar results are obtained using 2-methylfuran.

Mannich reactions I of 2-methylfuran have been reported to afford good yields of 2-N,N-dialkyaminomethyl-5-methylfuran using aqueous formaldehyde and secondary amines under