Genetic influences on mannan-binding lec
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Grith L. Sorensen; Inge Petersen; Steffen Thiel; Mogens Fenger; Kaare Christense
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Article
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2006
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John Wiley and Sons
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English
β 158 KB
## Abstract The lectin pathway of the complement system is activated when Mannanβbinding lectin (MBL) in complex with MASPβ2 binds microorganisms. Polymorphisms in both genes are responsible for low serum levels, which associate with increased risk of infection and autoimmune disease. The present s