## Abstract Frameshift mutations at coding mononucleotide repeats (cMNR) are frequent in highβmicrosatellite instability (MSIβH) cancers. Frameshift mutations in cMNR result in the formation of a premature termination codon (PTC) in the transcribed mRNA, and these abnormal mRNAs are generally degra
β¦ LIBER β¦
Manipulation of nonsense mediated decay identifies gene mutations in colon cancer Cells with microsatellite instability
β Scribed by Ionov, Yurij; Nowak, Norma; Perucho, Manuel; Markowitz, Sanford; Cowell, John K
- Book ID
- 110068259
- Publisher
- Nature Publishing Group
- Year
- 2004
- Tongue
- English
- Weight
- 189 KB
- Volume
- 23
- Category
- Article
- ISSN
- 0950-9232
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
Identification of frequently mutated gen
β
Nara Shin; Kwon Tae You; Hanna Lee; Won Kyu Kim; Meiying Song; Hee-Jung Choi; Hw
π
Article
π
2010
π
John Wiley and Sons
π
French
β 654 KB
Identifying candidate colon cancer tumor
β
Ivanov, I; Lo, K C; Hawthorn, L; Cowell, J K; Ionov, Y
π
Article
π
2006
π
Nature Publishing Group
π
English
β 322 KB
A novel missense mutation and frameshift
β
Hideo Orimo; Miyoko Ikejima; Eiitsu Nakajima; Mitsuru Emi; Takashi Shimada
π
Article
π
1998
π
Elsevier Science
π
English
β 205 KB
Identification of inactivating mutations
β
Michael R. Rossi; Lesleyann Hawthorn; Julie Platt; Tania Burkhardt; John K. Cowe
π
Article
π
2005
π
Elsevier Science
π
English
β 477 KB
Aberrant splicing of the ATM gene associ
β
Yosuke Ejima; Lichun Yang; Masao S. Sasaki
π
Article
π
2000
π
John Wiley and Sons
π
French
β 181 KB
π 2 views
Inherited mutations of the ATM gene are responsible for the human autosomal recessive disorder ataxia-telangiectasia (A-T) characterized by pleiotropic clinical manifestations. ATM mutations are also involved in the development of sporadic human cancers such as T-cell prolymphocytic leukemia and B-c