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Manipulating conformational equilibria in the lactose permease of Escherichia coli

✍ Scribed by Adam B. Weinglass; Melissa Sondej; H.Ronald Kaback

Book ID
115631581
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
305 KB
Volume
315
Category
Article
ISSN
0022-2836

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πŸ“œ SIMILAR VOLUMES

Ligand-Induced conformational changes in
Ligand-Induced conformational changes in the lactose permease of escherichia coli: Evidence for two binding sites
✍ Jianhua Wu; Stathis Frillingos; John Voss; H. Ronald Kaback πŸ“‚ Article πŸ“… 1994 πŸ› Cold Spring Harbor Laboratory Press 🌐 English βš– 848 KB

## Abstract By using a lactose permease mutant containing a single Cys residue in place of Val 331 (helix X), conformational changes induced by ligand binding were studied. With right‐side‐out membrane vesicles containing Val 331 β†’ Cys permease, lactose transport is inactivated by either __N__‐ethy