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Manifestation of atypical hemolytic uremic syndrome caused by novel mutations inMCP

✍ Scribed by Dana Provaznikova; Simon Rittich; Michal Malina; Tomas Seeman; Iuri Marinov; Magdalena Riedl; Ingrid Hrachovinova


Publisher
Springer
Year
2011
Tongue
English
Weight
274 KB
Volume
27
Category
Article
ISSN
0931-041X

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De novo gene conversion in the RCA gene
✍ Stefan Heinen; Pilar Sanchez-Corral; Michael S Jackson; Lisa Strain; Judith A. G πŸ“‚ Article πŸ“… 2006 πŸ› John Wiley and Sons 🌐 English βš– 315 KB

Many of the complement regulatory genes within the RCA cluster (1q32) have arisen through genomic duplication and the resulting high degree of sequence identity is likely to predispose to gene conversion events. The highest degree of identity is between the genes for factor H (CFH) and five factor H