Manganese(III) reactions in N-heterocycle synthesis: The preparation of substituted pyrrolidinones

✍ Scribed by David T. Davies; Neha Kapur; Andrew F. Parsons

• Book ID: 104259319
• Publisher: Elsevier Science
• Year: 1998
• Tongue: French
• Weight: 233 KB
• Volume: 39
• Category: Article
• ISSN: 0040-4039
• DOI: 10.1016/s0040-4039(98)00746-1

✦ Synopsis

The reaction of various N-acyl enamines with manganese(III) acetate in boiling methanol has been explored. This was shown to produce functionalised pyrrolidinones via a 5-endo-trig radical cyclisalion.