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Manganese Superoxide Dismutase Negatively Regulates the Induction of Apoptosis by 5-Fluorouracil, Peplomycin and γ-Rays in Squamous Cell Carcinoma Cells

✍ Scribed by Ueta, Eisaku ;Yoneda, Kazunori ;Yamamoto, Tetsuya ;Osaki, Tokio


Book ID
108581761
Publisher
Wiley (Blackwell Publishing)
Year
1999
Tongue
English
Weight
334 KB
Volume
90
Category
Article
ISSN
0910-5050

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Mn-SOD antisense upregulates in vivo apo
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ROIs and their scavengers are associated with apoptosis induction by anticancer drugs and ␥-rays, but the details have not been clarified. We examined the effect of transfection of Mn-SOD antisense on apoptosis by 5-FU, PLM, CDDP and ␥-rays using nu/nu mice. After inoculation of Mn-SOD antisense-tra