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Manganese effects in the liver following subacute or subchronic manganese chloride exposure in rats

✍ Scribed by Peili Huang; Chunxia Chen; Hui Wang; Guojun Li; Haiming Jing; Ying Han; Na Liu; Yang Xiao; Qiuhong Yu; Yuting Liu; Pengwen Wang; Zhixiong Shi; Zhiwei Sun

Book ID
116418449
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
954 KB
Volume
74
Category
Article
ISSN
0147-6513

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The purpose of this study was to evaluate the relative sensitivity of neonatal and adult CD rats to manganese-induced neurotoxicity. Identical oral manganese chloride (MnCl(2)) doses (0, 25, or 50 mg kg(-1) body wt. day(-1)) were given to neonatal rats throughout lactation (i.e. from postnatal day (