Mandibular cuniculatum carcinoma: Apropos of 3 cases and literature review

✍ Scribed by Yoann Pons; Siham Kerrary; Amanda Cox; Agnès Guerre; Chloé Bertolus; Françoise Gruffaz; Frédérique Capron; Patrick Goudot; Blandine Ruhin-Poncet

• Book ID: 102847625
• Publisher: John Wiley and Sons
• Year: 2010
• Tongue: English
• Weight: 559 KB
• Volume: 34
• Category: Article
• ISSN: 1043-3074
• DOI: 10.1002/hed.21493

✦ Synopsis

Abstract

Background

Cuniculatum carcinoma is a well‐differentiated form of squamous cell carcinoma that shares histologic characteristics with papillary squamous cell carcinoma and verrucous carcinoma. Cuniculatum carcinoma usually occurs on the plantar region, and only 16 cases involving the oral cavity have been described in the literature.

Methods

The authors have reported 3 cases of mandibular cuniculatum carcinoma. All of the patients were in a great deal of pain. Histologic diagnosis was difficult due to the presence of few cellular atypies. Clinical criteria, osseous lysis, and the coexistence of multiple intraosseous well‐differentiated, hyperkeratotic papillomatous lesions with few cellular atypies sign the diagnosis.

Results

No local recurrence has been reported after treatment with radical surgery alone.

Conclusion

The diagnosis is often delayed. Although cuniculatum carcinoma displays aggressive behavior locally, lymph node infiltration and metastasis are rare. The therapy of choice is surgical removal with free margins, after which the prognosis is excellent. © 2010 Wiley Periodicals, Inc. Head Neck, 2012