Management strategies for poor peripheral blood stem cell mobilization
β Scribed by Rainer Moog
- Book ID
- 116928707
- Publisher
- Elsevier Science
- Year
- 2008
- Tongue
- English
- Weight
- 140 KB
- Volume
- 38
- Category
- Article
- ISSN
- 1473-0502
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π SIMILAR VOLUMES
Hematopoietic stem cells circulate in the peripheral blood. These cells can be collected by apheresis techniques either in the unperturbed state, after mobilization following the administration of cytokines like G-CSF o r GM-CSF, or during the phase of early blood count recovery following chemothera
## Abstract Granulocyte colonyβstimulating factor (GCSF) is currently the most widely used cytokine for stem cell mobilization. There are few studies suggesting GCSF administration may induce activation of both coagulation and endothelial cells that could favor the developing of thrombotic events.