Management of squamous cell carcinoma of the floor of mouth

✍ Scribed by Drs. Lawrence W. Rodgers Jr.; Dr. Scott P. Stringer; William M. Mendenhall; James T. Parsons; Nicholas J. Cassisi; Rodney R. Million

• Publisher: John Wiley and Sons
• Year: 1993
• Tongue: English
• Weight: 397 KB
• Volume: 15
• Category: Article
• ISSN: 1043-3074
• DOI: 10.1002/hed.2880150104

✦ Synopsis

Between 1964 and 1987, 194

patients with previously untreated squamous cell carcinoma of the floor of mouth were managed at the University of Florida. A retrospective analysis was undertaken in order to evaluate the treatment results and associated complication rates. Surgery or irradiation alone was found to result in similar local control rates for stage I and II lesions, whereas more advanced tumors had better local control rates with a combination of surgery and irradiation. Radiotherapy had a higher incidence of minor and moderate complications, whereas a greater number of severe complications occurred after surgery. We recommend surgery for early lesions due to the lower overall incidence of associated complications. Despite a higher risk of severe complications, combination therapy is recommended for more advanced lesions due to improved local control as compared to single modality therapy.