Management of Refractory Acute Myeloid Leukemia: Re-induction Therapy or Straight to Transplantation?
β Scribed by E. J. Feldman; Usama Gergis
- Book ID
- 107540324
- Publisher
- Current Science Inc.
- Year
- 2011
- Tongue
- English
- Weight
- 94 KB
- Volume
- 7
- Category
- Article
- ISSN
- 1558-8211
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Fifty-four patients treated with daunorubicin, cytosine arabinoside and thioquanine for acute myeloid leukemia were randomly assigned to recieve oral lithium carbonate 1200 mg daily or no lithium. The duration of neutropenia (<0.5 x 109/L) was similar between controls (median 22.5 days) and patients
## Abstract ## BACKGROUND Imatinib mesylate is a selective tyrosine kinase inhibitor of cβabl, bcr/abl, cβkit, and plateletβderived growth factorβreceptor (PDGFβR). cβkit is expressed in most patients with acute myeloid leukemia (AML) and myelodysplastic syndrome (MDS) and PDGF has been implicated