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Management of nonresponse to rituximab in rheumatoid arthritis: Predictors and outcome of re-treatment

✍ Scribed by E. M. Vital; S. Dass; A. C. Rawstron; M. H. Buch; V. Goëb; K. Henshaw; F. Ponchel; P. Emery

Publisher: John Wiley and Sons
Year: 2010
Tongue: English
Weight: 186 KB
Volume: 62
Category: Article
ISSN: 0004-3591
DOI: 10.1002/art.27359

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## Abstract ## Objective Rituximab displays therapeutic benefits in the treatment of patients with rheumatoid arthritis (RA) resistant to tumor necrosis factor (TNF) blockade. However, the precise role of B cells in the pathogenesis of RA is still unknown. We undertook this study to investigate th