Management of hyponatremia seizures in children with hypertonic saline: A safe and effective strategy: Sarnaik AP, Meert K, Hackbarth R, et al Crit Care Med 19:758–762 Jun 1991
✍ Scribed by Stephen L Johnson
- Publisher
- Elsevier Science
- Year
- 1992
- Tongue
- English
- Weight
- 88 KB
- Volume
- 21
- Category
- Article
- ISSN
- 1097-6760
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✦ Synopsis
ABSTRACTS
three, or five injections of the same dose at weekly intervals. Equal members of animals from all three groups were sacrificed at three, six, and nine weeks after trauma, and the Achilles tendon from each was studied for histopathology and the amount of linear force required to rupture the isolated tendon. There was no significant difference in tendon strength between rats in the control group and those that received trauma and injection of hydrocortisione for all time intervals. However, at week six, tendon strength for the control group was significantly greater than for the group that had trauma but no injection. Histologic analysis of the tendons from all three groups revealed some variability, but it was of limited value. The authors conclude that local hydrocortisone injection has no deleterious effect on the rat Achilles tendon as measured biomechanically or histologically.