We describe the successful treatment of a pregnant patient with chronic myelogenous leukemia in chronic phase by using only leukapheresis. Following 20 leukapheresis procedures initiated during the 13th week of gestation and performed over approximately 7 weeks, the patients white blood cell count d
Management of familial hypertriglyceridemia during pregnancy with plasma exchange
β Scribed by Praveen Sivakumaran; Steven W. Tabak; Kimberly Gregory; Samuel H. Pepkowitz; Ellen B. Klapper
- Publisher
- John Wiley and Sons
- Year
- 2009
- Tongue
- English
- Weight
- 101 KB
- Volume
- 24
- Category
- Article
- ISSN
- 0733-2459
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β¦ Synopsis
Hypertriglyceridemia-induced pancreatitis is a serious complication of familial dyslipidemias. Hormonal influences during pregnancy can compromise otherwise controlled lipid levels in women with familial hypertriglyceridemia and predispose to pancreatitis leading to increased morbidity in both mother and fetus. We report the successful use of therapeutic plasma exchange (TPE) in the management of hypertriglyceridemia during pregnancy resulting in avoidance of pancreatitis and delivery of a healthy term infant. Thirteen TPEs were performed from 19 to 36 weeks gestation to maintain tight control of triglyceride levels.
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## Abstract Cyclosporine is commonly used as an immunosuppressive agent in both solid organ and bone marrow transplant. While used for graft rejection in organ transplantation, cyclosporine has been used to enable tolerance and for prevention of acute graftβversusβhost disease in bone marrow transp
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