Management of early-onset breast cancer and BRCA1 or BRCA2 status
โ Scribed by Jayant S Vaidya; Michael Baum
- Book ID
- 117281464
- Publisher
- The Lancet
- Year
- 2002
- Tongue
- English
- Weight
- 48 KB
- Volume
- 360
- Category
- Article
- ISSN
- 0140-6736
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
The recent discovery of the breast cancer-associated genes BRCA1 and BRCA2 has changed the clinical care provided to women at high risk of breast cancer. We will review what is currently known about the clinical management of patients who bear (or are suspected of bearing) mutations in either of the
The entire coding regions of BRCA1 and BRCA2 were screened for mutations by heteroduplex analysis in 51 Mexican breast cancer patients. One BRCA1 and one BRCA2 truncating mutation each was identified in the group of 32 (6%) early-onset breast cancer patients (< or =35 years). Besides these two likel