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Mammalian tyrosinase: Isozymic forms of the enzyme

✍ Scribed by Vincent J. Hearing; Thomas M. Ekel; Paul M. Montague


Book ID
103119278
Publisher
Elsevier Science
Year
1981
Tongue
English
Weight
414 KB
Volume
13
Category
Article
ISSN
0020-711X

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Two tyrosinase isozymes were purified from pigmented hamster melanoma and injected i.v. into rats. It was shown that while T1 (sialylated) isozyme survived in the circulation, native asialo (T2) isozyme and neuraminidase-desialylated T1 isozyme disappeared from the circulation in a few minutes. Desi