Mammalian Brain Development

✍ Scribed by Hugo F. Carrer, María J. Cambiasso (auth.), Damir Janigro (eds.)

• Publisher: Humana Press
• Year: 2009
• Tongue: English
• Leaves: 236
• Series: Contemporary Neuroscience
• Edition: 1
• Category: Library

✦ Synopsis

This book charts the way forward through the field of mammalian brain development, in which the integration of biological function can occur at all levels between the gene and the organism itself. Mammalian Brain Development examines the traditional "nature versus nurture" argument in the spectrum of brain development, discussing in particular sex differences in spatial perception ability, phenotype plasticity, disorders of brain development, Blood-Brain and placental barriers, chromosome abnormalities, as well as the use of imaging techniques. Geared toward neuroscientists, neurologists, pediatricians, pediatric psychiatrists, and neuroimmunologists, this volume paves the way toward the realization that the development of an individual is fundamentally an interaction between its genes and environment.

✦ Table of Contents

Front Matter....Pages i-xiv
Sexual Differentiation of the Brain: Genetic, Hormonal and Trophic Factors....Pages 1-15
Life at the Interface Between a Dynamic Environment and a Fixed Genome: Epigenetic Programming of Stress Responses by Maternal Behavior....Pages 17-39
Effects of Early Life Seizures and Anti-epileptic Drug Treatment on Human Brain Development in Human Models....Pages 41-52
Prenatal Development of the Human Blood-Brain Barrier....Pages 53-75
Seizure Propensity and Brain Development: A Lesson from Animal Models....Pages 77-104
Seizures and Antiepileptic Drugs: Does Exposure Alter Normal Brain Development in Animal Models?....Pages 105-132
Overview of Neural Mechanisms in Developmental Disorders....Pages 133-151
Drug Permeation Across the Fetal Maternal Barrier....Pages 153-170
In Vivo Imaging of Brain Development: Technologies, Models, Applications, and Impact on Understanding the Etiology of Mental Retardation....Pages 171-192
Congenital, Non-inheritable Chromosomal Abnormalities Responsible for Neurological Disorders....Pages 193-218
Erratum....Pages 228-228
Back Matter....Pages 219-227

✦ Subjects

Neurosciences; Human Genetics; Neurology; Neurobiology