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Mammalian aPKC/Par polarity complex mediated regulation of epithelial division orientation and cell fate

✍ Scribed by Vorhagen, Susanne; Niessen, Carien M.


Book ID
125887205
Publisher
Elsevier Science
Year
2014
Tongue
English
Weight
1022 KB
Volume
328
Category
Article
ISSN
0014-4827

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## Abstract **Background:** Recent studies have revealed that aPKC (atypical protein kinase C), PAR‐3 and PAR‐6 play indispensable roles in the regulation of various cell polarization events, from worms to mammals, suggesting that they comprise an evolutionarily conserved protein machinery which is