Mammalian Alkaloids: O-methylation of (S)- and (R)-dideoxynorlaudanosoline-1-carboxylic acid by catechol O-methyltransferase and identification of a yellow pigment obtained at physiological pH

Mammalian Alkaloids: O-Methylation of (±

Mammalian Alkaloids: O-Methylation of (±)-Norcoclaurine-1-carboxylic Acid and Related Isoquinolines Including (S)- and (R)-Norcoclaurine with 14C-Labeled S-Adenosyl-L-Methionine in Presence of Mammalian Catechol O-Methyltransferase

✍ Yasuo Sekine; Cyrns Crevelling; Maureen Bell; Arnold Brossi 📂 Article 📅 1990 🏛 John Wiley and Sons 🌐 German ⚖ 500 KB

### 9.1. 90) (5)-Norcoclaurine-I-carboxylic acid (5) and the derived dihydroisoquinolinone 6 (present as quinonemethide 6a at pH 7) afforded, on methylation with I4C-labeled S-adenosyl-L-methionine in the presence of mammalian catechol 0 methyitransferase, exclusively the 7-0-methylated congeners 7