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Malonaldehyde acts as a mitochondrial toxin: Inhibitory effects on respiratory function and enzyme activities in isolated rat liver mitochondria

✍ Scribed by Jiangang Long; Xuemin Wang; Hongxiang Gao; Zhi Liu; Changsheng Liu; Mingyong Miao; Jiankang Liu


Book ID
116718704
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
213 KB
Volume
79
Category
Article
ISSN
0024-3205

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## Abstract The influence of piperine on the enzymes and bioenergetic functions in isolated rat liver mitochondria and hepatocytes was studied. Piperine at lower concentrations (<50 ΞΌM) did not affect the RCR and ADP:O ratios, state 4 and 3 respirations supported by site‐specific substrates, viz. g