Malignant tumors of bone in children
β Scribed by Bradley L. Coley; Richard L. Peterson
- Book ID
- 119451679
- Publisher
- Elsevier Science
- Year
- 1939
- Tongue
- English
- Weight
- 312 KB
- Volume
- 15
- Category
- Article
- ISSN
- 1097-6833
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Nineteen patients with advanced malignant tumors, less than 20 years old were treated with intensive chemotherapy (vincristine 2 mg/m2 i.v. and adriamycin 60 mg/m2 i.v. on day - 7; cyclophosphamide 45 mg/kg i.v. on days -6 to -3), total body irradiation (TBI, 600 rads on day -1) and autologous bone
The application of intensive multimodality therapy has made possible salvage surgery in bone tumors. Reconstruction of the removed part of bone is the great problem, especially in fast-growing children. In three patients (two osteosarcomas and one Ewing's sarcoma), the tumor was confined to the prox