Malignant plasma cell tumors in human immunodeficiency virus-infected patients

✍ Scribed by Jay E. Gold; Lori Schwam; Antonio Castella; Sheldon B. Pike; Richard Opfell; Ralph Zalusky

• Publisher: John Wiley and Sons
• Year: 1990
• Tongue: English
• Weight: 689 KB
• Volume: 66
• Category: Article
• ISSN: 0008-543X
• DOI: 10.1002/1097-0142(19900715)66:2<363::aid-cncr2820660227>3.0.co;2-j

✦ Synopsis

The development of malignant neoplasms in patients with the acquired immune deficiency syndrome (AIDS) or with a positive human immunodeficiency virus (HIV) antibody test is a well known phenomenon. According to the guidelines from the Centers for Disease Control (Atlanta, GA), the presence of intermediate-grade or high-grade B-cell non-Hodgkin's lymphoma in HIV antibody-positive patients is considered a diagnostic criterion for AIDS. The authors describe two cases of malignant plasma cell tumors in two young HIV-infected patients. In light of this and other reports of plasma cell tumors in patients at risk for AIDS or with a positive HIV antibody test, the finding of another manifestation of B-cell neoplasia in these patients may enlarge the spectrum of AIDS-related tumors.