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Malignant hyperthermia in a patient with King Denborough syndrome lack of correlation with the RYR gene mutation

✍ Scribed by B. Echenne; F. Rivier; A. Roubertie; J. Lunardi; E.M. Chambaz


Book ID
117670726
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
128 KB
Volume
7
Category
Article
ISSN
0960-8966

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Malignant hyperthermia (MH) is a dominantly inherited pharmacogenetic condition that manifests as a life-threatening hypermetabolic reaction when a susceptible individual is exposed to common volatile anesthetics and depolarizing muscle relaxants. Although MH appears to be genetically heterogeneous,