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Malignant germ cell tumours of childhood: new associations of genomic imbalance

✍ Scribed by Palmer, R D; Foster, N A; Vowler, S L; Roberts, I; Thornton, C M; Hale, J P; Schneider, D T; Nicholson, J C; Coleman, N

Book ID
109999075
Publisher
Nature Publishing Group
Year
2007
Tongue
English
Weight
234 KB
Volume
96
Category
Article
ISSN
0007-0920

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Comparative genomic hybridization (CGH) was used to evaluate tissue specimens from 16 seminomas in order to elucidate the pathogenesis of germ cell tumours in males. A characteristic pattern of losses and gains within the entire genomes was detected in 94% of the seminomas by comparing the ratio pro