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Malignant fibrous histiocytoma of the brain in a six-year-old girl

✍ Scribed by Jaclyn A. Biegel; Giorgio Perilongo; Lucy B. Rorke; Annette H. Parmiter; Beverly S. Emanuel

Publisher
John Wiley and Sons
Year
1992
Tongue
English
Weight
440 KB
Volume
4
Category
Article
ISSN
1045-2257

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✦ Synopsis

Abstract

We have prepared karyotypes from a malignant fibrous histiocytoma (MFH) of the brain of a 6‐year‐old girl. Sporadic cases of MFH in the central nervous system have been reported. However, to our knowledge, this is the first central nervous system tumor to be subjected to cytogenetic analysis. The tumor demonstrated a complex karyotype, with a variety of numerical and structural abnormalities. Although no specific cytogenetic abnormality was observed, the karyotype of this case was similar to those reported for adult MFH of soft tissues.

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