Malignant Leydig cell tumors (LCT) are rare. Only 32 cases of malignant LCT (as evidenced by metastatic spread) were reported. Generally metastatic spread occurs within 2 years of the primary LCT, and the patient dies within 2 years of the discovery of metastatic disease. The tumor is highly resista
Malignant feminizing leydig cell tumor
β Scribed by Charles M. Shapiro; Anatole Sankovitch; Woo J. Yoon
- Publisher
- John Wiley and Sons
- Year
- 1984
- Tongue
- English
- Weight
- 921 KB
- Volume
- 27
- Category
- Article
- ISSN
- 0022-4790
No coin nor oath required. For personal study only.
β¦ Synopsis
A patient with a feminizing malignant Leydig cell tumor is presented. Hormonal assays revealed increased production of prolactin, estradial. and total estrogens. Eleven years after the onset of his disease he remains clinically well.
π SIMILAR VOLUMES
A 51-year-old man had a malignant Leydig cell tumor of the testis with elevation of serum estrone and endrostenedione as well as urine chorionic gonadotropin. The fine structural features of the neoplasm resembled those of nontumorous Leydig cells as well as cells of Leydig cell adenomas, except for
Dear Dr. Bedrossian: Leydig (interstitial) cell tumors are rare neoplasms accounting for 1-3% of all testicular tumors. Only 10% of these neoplasms will demonstrate malignant behavior, characterized by metastases to retroperitoneal lymph nodes, lung, and liver. While rare primary Leydig cell tumors