Malignant Bone Tumors

✍ Scribed by E. Grundmann (auth.), Prof. Dr. Ekkehard Grundmann (eds.)

• Publisher: Springer-Verlag Berlin Heidelberg
• Year: 1976
• Tongue: English
• Leaves: 288
• Series: Recent Results in Cancer Research / Fortschritte der Krebsforschung / Progrès dans les recherches sur le cancer 54
• Edition: 1
• Category: Library

✦ Synopsis

Bone Tumors - A Challenge for Cooperation E. GRUNDMANN Among the wide variety of human tumors, those of the skeletal system have an exceptional position in several respects. Above all, they are comparatively rare, and that is why reliable diagnostic criteria were compiled only recently, that is during the last three decades. It is only five years since the outlines of an international code of classi­ fication were traced. The code was applied and discussed critically and with varying results by several international working groups. Cer­ tain drawbacks are due to the broad and manifold spectrum of histolo­ gic manifestations in neoplastic bone. Even the best experts in dia­ gnostic histology would hardly be able to classify more than 85% of all bone tumors after the proposed code system. For quite a long time the osteoclastic giant cells, observed in almost any kind of bone tumor, have so much fascinated the histologist's eye that he was apt to pro­ claim the diagnosis "brown giant cell tumor" for almost any osteoclas­ tic tumor regardless of its benignity or malignancy. Nowadays the group of "giant cell tumors" though'restricted, still remains disputed in terms of malignancy and benignity. The problem will certainly not be settled in a definite way without extensive follow-up studies. In this context we may see actual progress in new regional. bone tumor registries being set up after the American example in many countries, among them the German Federal Republic.

✦ Table of Contents

Front Matter....Pages I-VIII
Bone Tumors — A Challenge for Cooperation....Pages 1-2
Comparative Pathology of Bone Tumors in Animals, with Particular Emphasis on the Dog....Pages 3-16
Bone Tumors Induced by Inhalation of 238 PuO 2 in Dogs....Pages 17-35
Experimental Induction of Bone Tumors by Short-Lived Bone-Seeking Radionuclides....Pages 36-49
Etiology of Childhood Bone Cancer: Epidemiologic Observations....Pages 50-62
The Endogenous Origin and Transmission of RNA Viral Genomes that Code for Cancer....Pages 63-91
Pathogenesis of Radiation and Virus-Induced Bone Tumors....Pages 92-103
The WHO Classification of Bone Tumors....Pages 104-108
Primary Malignancy, Secondary Malignancy and Semimalignancy of Bone Tumors....Pages 109-119
Common Errors Made by Pathologists in the Diagnosis of Bone Tumors....Pages 120-138
Aspiration (Puncture or Needle) Biopsy in Bone Lesions....Pages 139-144
Cytologic and Cytochemical Behavior of Primary Malignant Bone Tumors....Pages 145-156
Histochemical and Electron-Microscopic Aspects of Bone Tumor Diagnosis....Pages 157-165
Morphological, Biological, Immunological and Biochemical Studies on Bone Tumors of Animals and Man....Pages 166-184
Immunologic Aspects of Human Sarcomas....Pages 185-196
The Immune-Status in Patients with Bone and Soft-Tissue Sarcomas....Pages 197-205
Laboratory Models of Minimal Residual Cancer; Development and Preliminary Immunotherapy Studies....Pages 206-217
The Treatment of Malignant Bone Tumors by Conservative Surgery....Pages 218-220
Management of Osteogenic Sarcoma at the Mayo Clinic....Pages 221-230
Surgical Treatment of Solitary Bone Cysts....Pages 231-238
Resection of Malignant Bone Tumors....Pages 239-256
Giant-Cell Tumor and Chondrosarcomas: Grading, Treatment and Results (Studies of 209 and 131 Cases)....Pages 257-261
X-Ray Therapy of Primary Bone Tumors....Pages 262-270
Back Matter....Pages 271-282

✦ Subjects

Medicine/Public Health, general