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Male-Mediated Developmental Toxicity: Enhanced Susceptibility to Induced Teratogenesis in the Offspring of Male Mice Treated with Ethylnitrosourea

โœ Scribed by Tetsuji NAGAO


Book ID
111300655
Publisher
John Wiley and Sons
Year
1999
Tongue
English
Weight
844 KB
Volume
39
Category
Article
ISSN
0914-3505

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Male mice of inbred strain A/J were intraperitoneally treated with ethylnitrosourea (ENU). On day 64-82 posttreatment, the males were mated with untreated virgin females of the same strain. Copulation involved sperm that were spermatogonial stem cells at the time of treatment. On day 18 of gestation