MALDI-TOF Mass Spectrometry as a Powerful Tool to Study Enzymatic Processing of DNA Lesions Inserted into Oligonucleotides

A study of the glutathione metaboloma pe

A study of the glutathione metaboloma peptides by energy-resolved mass spectrometry as a tool to investigate into the interference of toxic heavy metals with their metabolic processes

✍ Federico Maria Rubino; Marco Pitton; Gabri Brambilla; Antonio Colombi 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 English ⚖ 453 KB

## Abstract To better understand the fragmentation processes of the metal–biothiol conjugates and their possible significance in biological terms, an energy‐resolved mass spectrometric study of the glutathione conjugates of heavy metals, of several thiols and disulfides of the glutathione metabolom