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MALDI imaging mass spectrometry for direct tissue analysis: a new frontier for molecular histology

✍ Scribed by Axel Walch; Sandra Rauser; Sören-Oliver Deininger; Heinz Höfler


Publisher
Springer
Year
2008
Tongue
English
Weight
879 KB
Volume
130
Category
Article
ISSN
1432-119X

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## Abstract MALDI‐imaging mass spectrometry (IMS) has been shown to be a powerful tool to study drug distributions in organ tissue as well as whole animal bodies. Nevertheless, not all drugs are amenable to MALDI while others may be limited by poor sensitivity poor sensitivity. The use of chemical