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MAL promoter hypermethylation as a novel prognostic marker in gastric cancer

โœ Scribed by Buffart, T E; Overmeer, R M; Steenbergen, R D M; Tijssen, M; van Grieken, N C T; Snijders, P J F; Grabsch, H I; van de Velde, C J H; Carvalho, B; Meijer, G A


Book ID
109999869
Publisher
Nature Publishing Group
Year
2008
Tongue
English
Weight
152 KB
Volume
99
Category
Article
ISSN
0007-0920

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## Abstract ## BACKGROUND Methylation of CpG islands in the promoter and upstream coding regions has been identified as a mechanism for transcriptional inactivation of tumor suppressor genes. The purpose of the current study was to determine the correlation between the aberrant promoter methylatio