Making a good model better - evaluation of the NSW Combined Family Cancer Clinic meetings

Pre-clinical evaluation of the Gastrimmu

Pre-clinical evaluation of the Gastrimmune immunogen alone and in combination with 5-fluorouracil/leucovorin in a rat colorectal cancer model

✍ Susan A. Watson; Dov Michael; Timothy A. Justin; Stephen Grimes; Teresa M. Morri 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 French ⚖ 135 KB 👁 2 views

Mature and post-translational precursor gastrin forms are growth factors for colorectal tumours. The immunogen Gastrimmune is composed of the amino terminus of gastrin-17 linked to diphtheria toxoid and raises antibodies in situ which neutralise amidated and glycine-extended gastrin-17. The aim of t