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Major regulators of microRNAs biogenesis Dicer and Drosha are down-regulated in endometrial cancer

✍ Scribed by Anna Torres; Kamil Torres; Tomasz Paszkowski; Barbara Jodłowska-Jędrych; Tomasz Radomański; Andrzej Książek; Ryszard Maciejewski


Book ID
107693939
Publisher
S. Karger AG
Year
2011
Tongue
English
Weight
999 KB
Volume
32
Category
Article
ISSN
1010-4283

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## Abstract ## BACKGROUND Imprinted tumor suppressor genes may be particularly important in the pathogenesis of ovarian cancer. Two imprinted genes, paternally expressed 3 (__PEG3__) and aplasia Ras homologue member I (__ARHI__), are the most frequently down‐regulated in ovarian cancers on gene ex