Major histocompatibility complex: from genes to function
โ Scribed by Denis J Moss; Rajiv Khanna
- Publisher
- Elsevier Science
- Year
- 1999
- Tongue
- English
- Weight
- 181 KB
- Volume
- 20
- Category
- Article
- ISSN
- 0167-5699
No coin nor oath required. For personal study only.
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## Major histocompatibility complex genes determine natural killer cell tolerance Murine natural killer (NK) cell subsets, as defined by expression of members of the Ly49 gene family, discriminate target cells expressing different major histocompatibility complex (MHC) class I alleles. For example
The human major histocompatibility complex (MHC), on the short arm of chromosome 6, represents one of the most extensively characterised regions of the human genome. This -4 Mb segment of DNA contains genes encoding the polymorphic MHC class I and class I1 molecules which are involved in antigen pre