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Major Histocompatibility Complex Class II (MHC II) Deficiency in a Child with Panhypogammaglobulinemia and Lymphopenia

✍ Scribed by Bailey, A.E.; Bleesing, J.J.H.; Jones, S.M.; Perry, T.T.; Nagarajan, U.M.; Scurlock, A.M.

Book ID
119279013
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
50 KB
Volume
119
Category
Article
ISSN
1097-6825

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## Abstract In this report we show that the major histocompatibility complex (MHC) class II‐negative thymus of a bare lymphocyte syndrome (BLS) patient contains a reduced CD4^+^ CD8^βˆ’^ T cell population when compared to thymocytes derived from a MHC class II‐expressing thymus. Of these CD4^+^ CD8^βˆ’