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Major depressive disorder and white matter abnormalities: A diffusion tensor imaging study with tract-based spatial statistics

✍ Scribed by Tuula Kieseppä; Mervi Eerola; Riitta Mäntylä; Tuomas Neuvonen; Veli-Pekka Poutanen; Katariina Luoma; Annamari Tuulio-Henriksson; Pekka Jylhä; Outi Mantere; Tarja Melartin; Heikki Rytsälä; Maria Vuorilehto; Erkki Isometsä

Book ID
113666776
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
997 KB
Volume
120
Category
Article
ISSN
0165-0327

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Loss of white matter integrity in major depressive disorder: Evidence using tract-based spatial statistical analysis of diffusion tensor imaging
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## Abstract White matter (WM) has been shown to be affected in elderly patients with major depressive disorders (MDD). There is only limited evidence of WM structural abnormalities in nongeriatric MDD patients. This study investigates WM microstructural integrity in nongeriatric MDD patients recrui