Formulations that produce supersaturated solutions after their oral administration have received increased attention as a means to improve bioavailability of poorly watersoluble drugs. Although it is widely recognized that excipients can prolong supersaturation, the mechanisms by which these benefic
β¦ LIBER β¦
Maintenance of supersaturation II: Indomethacin crystal growth kinetics versus degree of supersaturation
β Scribed by Patel, Dhaval D.; Anderson, Bradley D.
- Book ID
- 120166244
- Publisher
- John Wiley and Sons
- Year
- 2013
- Tongue
- English
- Weight
- 593 KB
- Volume
- 102
- Category
- Article
- ISSN
- 0022-3549
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## Abstract Slow barium chromate precipitation was studied in wellβstirred solutions β final concentration 0.002 mole 1^β1^ β at 20Β°C at mixing rates varying from 0.2 to 2 Β· 10^6^ mole 1^β1^ sec^β1^; the kinetics of the crystal growth process were studied by chemical analysis and by optical microsc