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Maintenance of MHC polymorphism

โœ Scribed by HUGHES, AUSTIN L.; NEI, MASTOSHI


Book ID
109779504
Publisher
Nature Publishing Group
Year
1992
Tongue
English
Weight
269 KB
Volume
355
Category
Article
ISSN
0028-0836

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There is unwarranted satisfaction with the view that MHC polymorphism evolved because there was a selective advantage in having a variety of MHC proteins to bind a variety of peptide subsets for presentation to T cells. While this may, in part, explain its maintainance, polymorphism may have evolved