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Maintenance of memory CTL responses by T helper cells and CD40-CD40 ligand: antibodies provide the key

✍ Scribed by M. F. Bachmann; Lukas Hunziker; R. M. Zinkernagel; T. Storni; M. Kopf


Publisher
John Wiley and Sons
Year
2004
Tongue
English
Weight
26 KB
Volume
34
Category
Article
ISSN
0014-2980

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Maintenance of memory CTL responses by T
✍ Martin F. Bachmann; Lukas Hunziker; Rolf M. Zinkernagel; Tazio Storni; Manfred K πŸ“‚ Article πŸ“… 2004 πŸ› John Wiley and Sons 🌐 English βš– 356 KB

Cytotoxic T lymphocytes (CTL) are essential for control of primary infections by many pathogens and in particular by non-cytopathic viruses. It has been proposed that long-term maintenance of CTL memory and control of lymphocytic choriomeningitis virus (LCMV) is dependent upon the presence of T help