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Maintenance of cytochrome P450 content and phase I and phase II enzyme activities in trout hepatocytes cultured as spheroidal aggregates

โœ Scribed by J.-P. Cravedi; A Paris; G. Monod; A. Devaux; G. Flouriot; Y. Valotaire


Book ID
116151702
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
718 KB
Volume
113
Category
Article
ISSN
0742-8413

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## Abstract The principal objectives of our study were to ascertain whether sulforaphane, at dietary levels of intake, modulates rat hepatic cytochrome P450 and phase II enzyme systems and to evaluate the impact of such changes in the chemopreventive activity of this isothiocyanate. Animals were ex