Intermittent treatment with human parathyroid hormone (1-34) ] stimulates bone formation and increases cancellous bone mass in ovariectomized (OW) rats. But PTH-induced cancellous bone rapidly disappears upon cessation of treatment. The fate of cortical bone treated by PTH has not been well characte
✦ LIBER ✦
Maintenance of bone mineral density of femoral cortex in ovariectomized rats after withdrawal of concurrent administration of human parathyroid hormone (1–34) and incardronate disodium (YM175)
✍ Scribed by Liu Zhang; Hideaki E. Takahashi; Tatsuhiko Tanizawa; Naoto Endo; Noriaki Yamamoto
- Publisher
- Springer
- Year
- 1997
- Tongue
- English
- Weight
- 693 KB
- Volume
- 15
- Category
- Article
- ISSN
- 0914-8779
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To evaluate the potential use of a combination of parathyroid hormone (PTH) and estrogen as therapy for osteoporosis, we examined the effects of combined and separate administration of low-dose PTH and estradiol in ovariectomized rats with established osteopenia. Ovariectomized rats were untreated f