𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Magnetosonoporation: Instant magnetic labeling of stem cells

✍ Scribed by Bensheng Qiu; Daohai Xie; Piotr Walczak; Xubin Li; Jesus Ruiz-Cabello; Satoshi Minoshima; Jeff W.M. Bulte; Xiaoming Yang

Book ID
102532995
Publisher
John Wiley and Sons
Year
2010
Tongue
English
Weight
335 KB
Volume
63
Category
Article
ISSN
0740-3194

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

The purpose of this study was to develop an instant MR cell labeling technique, called magnetosonoporation. First, a magnetosonoporation apparatus was successfully established for MR labeling of stem cells. Then, the safety of this new cell labeling approach was confirmed by evaluation of cell viability, proliferation, and differentiation of magnetosonoporation‐labeled and unlabeled C17.2 neural stem cells. Subsequently, the feasibility of using in vivo MRI to detect magnetosonoporation/Feridex‐labeled stem cells was validated in living animals and confirmed by histologic correlation. The magnetosonoporation technique is expected to be convenient, efficient, and safe for future clinical application of MRI‐guided cell therapies. Magn Reson Med 63:1437–1441, 2010. Β© 2010 Wiley‐Liss, Inc.

πŸ“œ SIMILAR VOLUMES

Instant MR labeling of stem cells using
Instant MR labeling of stem cells using magnetoelectroporation
✍ P. Walczak; D. A. Kedziorek; A. A. Gilad; S. Lin; J. W. M. Bulte πŸ“‚ Article πŸ“… 2005 πŸ› John Wiley and Sons 🌐 English βš– 658 KB

## Abstract For cellular MR imaging, conventional approaches to intracellular magnetic labeling of nonphagocytic cells rely on the use of secondary compounds such as transfection agents and prolonged incubation of cells. Magnetoelectroporation (MEP) was investigated as an alternative method to achi

Labeling of Adipose-Derived Stem Cells b
Labeling of Adipose-Derived Stem Cells by Oleic-Acid-Modified Magnetic Nanoparticles
✍ Lian Cen; Koon Gee Neoh; Jian Sun; Feixiong Hu; Wei Liu; Lei Cui; Yilin Cao πŸ“‚ Article πŸ“… 2009 πŸ› John Wiley and Sons 🌐 English βš– 735 KB

## Abstract The in vivo tracking of adipose derived stem cells (ASCs) is of essential concern when they are used as seed cells in tissue engineering. This study explores the feasibility of using magnetic nanoparticles (MNs), a type of contrast agents in magnetic resonance imaging (MRI), to label AS