## Abstract Goodpasture syndrome is a lifeβthreatening autoimmune kidney and pulmonary disease that is characterized by pulmonary hemorrhage, renal failure, and the presence of autoantibodies against glomerular basement membrane (GBM) by indirect fluorescent antibody (IFA) techniques. In 1988, thes
Magnetic solid-phase enzyme immunoassay for the detection of anti-glomerular basement membrane antibodies
β Scribed by E. Druet; P. Mahieu; J.M. Foidart; P. Druet
- Book ID
- 118898630
- Publisher
- Elsevier Science
- Year
- 1982
- Tongue
- English
- Weight
- 437 KB
- Volume
- 48
- Category
- Article
- ISSN
- 0022-1759
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## Abstract A solid phase enzyme immunoassay (EIA) detected antiβdoubleβstranded (ds) DNA antibodies in 88% of sera from patients classified clinically as having active systemic lupus erythematosus (SLE) without renal symptoms and 93% with renal disease. Fiftyβsix percent of sera from patients with
Goodpasture's disease is characterized by rapidly progressive glomerulonephritis, often accompanied by pulmonary hemorrhage, in association with deposition of antibodies in a linear pattern on the glomerular basement membrane (GBM). The diagnosis of Goodpasture's disease in patients with acute renal