𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Magnetic resonance profiling of human skin in vivo using GARField magnets

✍ Scribed by P.J. McDonald; A. Akhmerov; L.J. Backhouse; S. Pitts

Publisher
John Wiley and Sons
Year
2005
Tongue
English
Weight
189 KB
Volume
94
Category
Article
ISSN
0022-3549

No coin nor oath required. For personal study only.

✦ Synopsis

It is shown that one-dimensional magnetic resonance imaging (MRI-profiling) of human forearm and side-of-hand skin in vivo is possible using GARField magnets. Strong profile contrast originating from differing molecular mobility is seen for stratum corneum and viable epidermis. The first in vivo spatially-resolved field-gradient measurements of water self-diffusivity, D, in the stratum corneum (2.0 x 10(-6) cm(2)/s) and viable epidermis (8.5 x 10(-6) cm(2)/s) are reported. Also reported are spatially resolved measurements of the (1)H spin-lattice relaxation time, T(1), the spin-spin relaxation time, T(2). It is further shown that the application of moisturizing agents to the skin noticeably affects the profiles. However, universal behavior is not seen as both signal increases and decreases are observed dependent on agent and volunteer.

πŸ“œ SIMILAR VOLUMES

GARField magnetic resonance profiling of
GARField magnetic resonance profiling of the ingress of model skin-care product ingredients into human skin in vitro
✍ L. Backhouse; M. Dias; J.P. Gorce; J. Hadgraft; P.J. McDonald; J.W. Wiechers πŸ“‚ Article πŸ“… 2004 πŸ› John Wiley and Sons 🌐 English βš– 152 KB πŸ‘ 1 views

A preliminary study of the ingress of mineral oil, decanol, and glycerine into samples of human abdominal skin tissue in vitro made using magnetic resonance profiling with a GARField magnet is reported. Two layers, each circa 50 mm thick and attributed to stratum corneum and viable epidermis, are sp

Magnetic resonance microimaging of human
Magnetic resonance microimaging of human skin vasculature in vivo at 3 Tesla
✍ Elmar Laistler; Robert Loewe; Ewald Moser πŸ“‚ Article πŸ“… 2011 πŸ› John Wiley and Sons 🌐 English βš– 375 KB πŸ‘ 1 views

## Abstract MRI can be used to investigate human skin microvasculature in vivo, provided adequate spatial resolution. Therefore, the sensitivity of the experiment has to be optimized to achieve sufficient signal‐to‐noise ratio (SNR) within reasonable measurement time to minimize motion artifacts, i

Metabolic profiles of human brain tumors
Metabolic profiles of human brain tumors using quantitative in vivo 1H magnetic resonance spectroscopy
✍ F.A. Howe; S.J. Barton; S.A. Cudlip; M. Stubbs; D.E. Saunders; M. Murphy; P. Wil πŸ“‚ Article πŸ“… 2003 πŸ› John Wiley and Sons 🌐 English βš– 252 KB πŸ‘ 1 views

## Abstract Proton spectroscopy can noninvasively provide useful information on brain tumor type and grade. Short‐ (30 ms) and long‐ (136 ms) echo time (TE) ^1^H spectra were acquired from normal white matter (NWM), meningiomas, grade II astrocytomas, anaplastic astrocytomas, glioblastomas, and met

In vivo magnetic resonance spectroscopy
In vivo magnetic resonance spectroscopy of human fetal neural transplants
✍ Brian D. Ross; Tuan Q. Hoang; Stefan BlΓΌml; David Dubowitz; Oleg V. Kopyov; Dean πŸ“‚ Article πŸ“… 1999 πŸ› John Wiley and Sons 🌐 English βš– 608 KB

To better define the survival and cellular composition of human fetal neurotransplants in vivo, we performed quantitative 1 H MRS to determine the concentration of the neuronal amino acid [N-acetylaspartate] within MRI-visible grafts. In all, 71 grafts in 38 patients [24 Parkinson's disease (PD), 14

In vivo spectroscopic magnetic resonance
In vivo spectroscopic magnetic resonance imaging using estimation theory
✍ Albert Macovski; D. Spielman πŸ“‚ Article πŸ“… 1986 πŸ› John Wiley and Sons 🌐 English βš– 434 KB πŸ‘ 1 views

The ability to map spectroscopic components for in vivo application is a highly desirable goal. Thusfar it has been unavailable because of the low SNR inherent in the measurement of each voxel. In this paper we deal with this low SNR in two ways. First, estimation theory, using a priori data, is use