Magnetic resonance iron-free nodules in genetic hemochromatosis
β Scribed by Dominique Guyader; Yves Gandon; Thierry Sapey; Bruno Turlin; Michel H Mendler; Pierre Brissot; Yves Deugnier
- Book ID
- 119396093
- Publisher
- Nature Publishing Group
- Year
- 1999
- Tongue
- English
- Weight
- 532 KB
- Volume
- 94
- Category
- Article
- ISSN
- 0002-9270
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Hemochromatosis (HC), the common inherited disorder in iron metabolism, affects at least 1 in 300 Caucasians. The disorder causes inappropriately high iron absorption and accumulation of excess iron in the parenchymal cells of the major organs of the body. The gene responsible for HC has recently be
Sublobular nodules of hepatocytes free of iron or exhibiting much less iron than the surrounding parenchyma, referred to in this study as iron-free-foci, are frequently found in the livers of patients with genetic hemochromatosis complicated by hepatocellular carcinoma. To test the hypothesis that s