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Magnetic resonance imaging on an NMR spectrometer. An experiment for the physical chemistry laboratory

✍ Scribed by Wayne E. Steinmetz; Cyrus R. Maher

Publisher
John Wiley and Sons
Year
2007
Tongue
English
Weight
148 KB
Volume
30A
Category
Article
ISSN
1546-6086

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✦ Synopsis

Abstract

We converted a conventional Fourier‐transform NMR spectrometer into an MRI imager by installing a triple‐axis gradient probe and medical imaging software. This arrangement permits imaging of materials that fit into a 5‐mm NMR tube to a resolution of 0.05 mm or better. The experiment introduces the student to the physical principles underlying MRI such as gradients, spin echoes, multidimensional spectroscopy, and relaxation. Students employ a multi‐slice‐multi‐echo (MSME) method to image a biological specimen and measure the transverse relaxation time, T~2~, of water in selected regions of interest. © 2007 Wiley Periodicals, Inc. Concepts Magn Reson Part A 30A: 133–139, 2007

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